CONTROL-T PUBLICATIONS

Metabolism is the Tie: The Bertalanffy-type Cancer Growth Model as Common Denominator of Various Modelling Approaches
Diebner HH, Zerjatke T, Griehl M, Roeder I.
Biosystems, Mar 29, 167:1-23, 201810.1016/j.biosystems.2018.03.004

Actionable perturbations of damage responses by TCL1/ATM and epigenetic lesions form the basis of T-PLL.
A. Schrader, G. Crispatzu, S. Oberbeck, P. Mayer, S. Pützer, J. von Jan, E. Vasyutina, K. Warner, N. Weit, N. Pflug, T. Braun, E.I. Andersson,B. Yadav, A. Riabinska, B. Maurer, M.S. Ventura Ferreira, F. Beier, J. Altmüller, M. Lanasa, C.D. Herling , T. Haferlach, S. Stilgenbauer, G. Hopfinger, M. Peifer, T.H. Brümmendorf, P. Nürnberg, K.S.J. Elenitoba-Johnson, S. Zha, M. Hallek, R. Moriggl, H.C. Reinhardt, M.-H. Stern, S. Mustjoki, S. Newrzela, P. Frommolt, M. Herling.
Nature Communications, 9, Article number: 697, 2018. doi:10.1038/s41467-017-02688-6

SAMHD1 is recurrently mutated in T-cell prolymphocytic leukemia.
Johansson P, Klein-Hitpass L, Choidas A, Habenberger P, Mahboubi B, Kim B, Bergmann A, Scholtysik R, Brauser M, Lollies A, Siebert R, Zenz T, Dührsen U, Küppers R, Dürig J.
Blood Cancer J., 8, Article number: 11, 2018. doi:10.1038/s41408-017-0036-5

TET2 mutations in B cells of patients affected by angioimmunoblastic T cell lymphoma.
Schwartz FH, Cai Q, Fellmann E, Hartmann S, Mäyränpää MI, Karjalainen-Lindsberg M-L, Sundström C, Scholtysik R*, Hansmann M-L*, Küppers R*.
J. Pathol 242, 129-133, 2017. (*shared senior authors). https://doi.org/10.1002/path.4898

Concepts in mature T-cell lymphomas – highlights from an international joint symposium on T-cell immunology and oncology.
Marco Herling, Benjamin Rengstl, René Scholtysik, Sylvia Hartmann, Ralf Küppers, Martin-Leo Hansmann, Hans H. Diebner, Ingo Roeder, Hinrich Abken, Sebastian Newrzela, Jörg Kirberg.
Leukemia & Lymphoma, 58(4), 2017. https://doi.org/10.1080/10428194.2016.1222381

Tumor infiltrating HLA-matched CD4+ T cells retargeted against Hodgkin and Reed-Sternberg cells.
Rengstl B, Schmid F, Weiser C, Döring C, Heinrich T, Warner K, Becker PS, Wistinghausen R, Kameh-Var S, Werling E, Seidl C, Hartmann S, Abken H, Küppers R, Hansmann M-L, Newrzela S.
Oncoimmunol, 5, e1160186, 2016. https://doi.org/10.1080/2162402X.2016.1160186

Novel IGH and MYC translocation partners in diffuse large B cell lymphomas.
Otto C, Scholtysik R, Schmitz R, Kreuz M, Becher C, Hummel M, Rosenwald A, Trümper L, Klapper W, Siebert R, Küppers R, for the "Molecular Mechanisms in Malignant Lymphomas" network project.
Genes Chrom Cancer, 55, 932-943, 2016. https://doi.org/10.1002/gcc.22391

Finding small somatic structural variants in exome sequencing data: a machine learning approach.
Kuhn M, Stange T, Herold S, Thiede C, Roeder I
Comput. Stat. 2016. https://doi.org/10.1007/s00180-016-0674-2

CD1d-restricted peripheral T cell lymphoma in mice and humans.
Bachy E, Urb M, Chandra S, Robinot R, Bricard G, de Bernard S, Traverse-Glehen A, Gazzo S, Blond O, Khurana A, Baseggio L, Heavican T, Ffrench M, Crispatzu G, Mondière P, Schrader A, Taillardet M, Thaunat O, Martin N, Dalle S, Le Garff-Tavernier M, Salles G, Lachuer J, Hermine O, Asnafi V, Roussel M, Lamy T, Herling M, Iqbal J, Buffat L, Marche PN, Gaulard P, Kronenberg M, Defrance T, Genestier L.
J. Exp. Med. 2016 Apr 11. https://doi.org/10.1084/jem.20150794

Re-activation of mitochondrial apoptosis inhibits T-cell lymphoma survival and treatment resistance.
Spinner S, Crispatzu G, Yi JH, Munkhbaatar E, Mayer P, Höckendorf U, Müller N, Li Z, Schader T, Bendz H, Hartmann S, Yabal M, Pechloff K, Heikenwalder M, Kelly GL, Strasser A, Peschel C, Hansmann ML, Ruland J, Keller U, Newrzela S, Herling M, Jost PJ.
Leukemia. 2016 Mar 8. https://doi.org/10.1038/leu.2016.49

An evolutionary stability perspective on oncogenesis control in mature T-cell populations.
Diebner HH, Kirberg J, Roeder I.
J. Theor. Biol. 2015 Nov 5. https://doi.org/10.1016/j.jtbi.2015.10.033

Are we improving the outcome for patients with T-cell prolymphocytic leukemia by allogeneic stem cell transplantation? (editorial)
Herling M.
Eur. J. Haematol. 94, 191-2, 2015. http://dx.doi.org/10.1111/ejh.12462

Integrated genomic sequencing reveals mutational landscape of T-cell prolymphocytic leukemia.
Kiel MJ, Velusamy T, Rolland D, Sahasrabuddhe AA, Chung F, Bailey NG, Schrader A, Li B, Jun Z. Li JZ, Ozel AB, Betz BL, Miranda RN, Medeiros LJ, Zhao L, Herling M, Lim MS, Elenitoba-Johnson KJS.
Blood 124, 1460-72, 2014. https://doi.org/10.1182/blood-2014-03-559542

Vitamin D controls apoptosis and proliferation of cutaneous T cell lymphoma cells. (letter)
Mrotzek C, Felcht M, Sommer A, Schrader A, Klemke CD, Herling M, Schlaak M, Fabri M.
Exp. Dermatol. 24, 798-800, 2015. https://doi.org/10.1111/exd.12746

A novel immunohistochemical classifier to distinguish Hodgkin lymphoma from ALK anaplastic large cell lymphoma.
Döring C, Hansmann ML, Agostinelli C, Piccaluga PP, Facchetti F, Pileri S, Küppers R, Newrzela S, Hartmann S.
Mod. Pathol. 2014 Mar 14. https://doi.org/10.1038/modpathol.2014.44

Mathematical modeling of oncogenesis control in mature T-cell populations.
Gerdes S, Newrzela S, Glauche I, von Laer D, Hansmann M-L, Roeder I.
Frontiers in Immunology 2013 Nov 21. https://doi.org/10.3389/fimmu.2013.00380

T-cell receptor signaling in peripheral T-cell lymphoma - a review of patterns of alterations in a central growth regulatory pathway.
Warner K, Weit N, Crispatzu G, Admirand J, Jones D, Herling M.
Curr. Hematol. Malig. Rep. 2013 Sep 8. https://doi.org/10.1007/s11899-013-0165-2

Models for mature T-cell lymphomas - A critical appraisal of experimental systems and their contribution to current T-cell tumorigenic concepts.
Warner K, Crispatzu G, Al-Ghaili N, Weit N, Florou V, You MJ, Newrzela S, Herling M.
Crit. Rev. Oncol. Hematol. 2013 Aug 20. http://dx.doi.org/10.1016/j.critrevonc.2013.07.014